module specification

The module studies the gross structure and ultrastructure of normal cells and tissues and the structural changes which may occur during disease (infectious and genetic causes); the principles and applications of laboratory diagnosis including aspects of QA and QC. Students’ will further develop their immunological, molecular, cellular visualisation and imaging techniques in the laboratory in practical sessions. Theoretical and practical problems will be employed to assist students in the development of their analytical and problem solving capabilities. Case studies will be examined to give students practice in diagnosis.

This module focuses on human pathology involving the evaluation of structural and functional changes in tissues brought about by  infection, inflammation, trauma and neoplasia. Selected examples  will be studied in depth to explore the underlying causes as well as the  pathophysiological features of disease.

This module will cover clinical pathology  including pathophysiological features of diseases and their cause (e.g. infection, inflammation, neoplasia).
Practical exercises will involve tissue identification, reviewing diseased tissue and immunological techniques.
(LO1-3)

Students will be provided with the opportunity to acquire knowledge through a programme of lectures, problem-solving tutorial sessions, laboratory based practical exercises and on-line exercises. Students’ ability to make critical evaluations will be developed through analysis of source material and case studies supported by tutorial material. Students ability to attain and critically evaluate data, and scrutinise the data through problem solving activities will be developed through laboratory based exercises. Students will be expected to reflect on taught material in order to demonstrate their understanding of the principles and practices of pathology.

On successful completion of this module students will be able to:

1.  Demonstrate knowledge of  a range of pathological states in cells and tissues and their underlying causes and assess  the pathophysiological features  of diseased tissues and organs, and apply the interpretation of laboratory results in diagnosing disease.
2. Appraise the application of  therapeutic and prophylactic measures and understand the use of laboratory investigations to integrate clinical diagnosis and treatment of disease.
3.  Work individually and as a member of a team in performing and evaluating immunological, molecular and cellular laboratory diagnostic procedures.

The module will be summatively assessed by means of one coursework component and one time constrained unseen examination. The practical report will assess the ability to gather and interpret data from experiments using diagnostic techniques. The unseen exam will assess knowledge of the subject and its application.

Summative assessment of the practical report will be given within three weeks of the hand-in date.  Practical results are also discussed in tutorials which also help to prepare students for summative assessment in the practical report.

To pass the module, students need to achieve a minimum aggregate mark of 40%. There will be an attendance requirement for the practical sessions. If the module is passed on reassessment, then the maximum mark awarded will be 40%.

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Journals:
Clinical Microbiology Reviews
Infection and Immunity
International Journal of Medical Microbiology
Journal of Medical Microbiology
Reviews in Medical Microbiology
Internet:
Centers for Disease Control and Prevention: www.cdc.gov
Federation of European Microbiological Societies: www.fems-microbiology.org
Health Protection Agency: www.hpa.org.uk
Microbe World: www.microbeworld.org
Microbes Info: www.microbes.info
Microbiology On-line: www.microbiologyonline.org.uk
Society for General Microbiology: www.socgenmicrobiol.org.uk
World Health Organization: www.who.int/en