DI5003 - Metabolic Biochemistry for Dietitians (2017/18)
| Module specification | Module approved to run in 2017/18 | ||||||||||||||||||||||||||||
| Module title | Metabolic Biochemistry for Dietitians | ||||||||||||||||||||||||||||
| Module level | Intermediate (05) | ||||||||||||||||||||||||||||
| Credit rating for module | 30 | ||||||||||||||||||||||||||||
| School | School of Human Sciences | ||||||||||||||||||||||||||||
| Total study hours | 300 | ||||||||||||||||||||||||||||
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| Assessment components |
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| Running in 2017/18(Please note that module timeslots are subject to change) |
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Module summary
This module focuses on understanding key principles of metabolism and nutritional metabolism. These principles are illustrated through study of the major metabolic pathways, the measurement, transport, storage, metabolism and excretion of macro and micronutrients and the application to health and disease.
Prior learning requirements
DI4005 Human Nutrition for Dietitians
DI4004 Cellular and Molecular Systems for Dietitians
Module aims
The aims of this module are aligned with the qualification descriptors within the Quality Assurance Agency’s Framework for Higher Education Qualifications. Specifically it aims to provide an understanding of the principles of metabolism and nutritional metabolism to encourage an appreciation of the diversity and interconnection of metabolic pathways, relate these to nutritional status and to stimulate an understanding of the applicability of metabolism in a broad range of biological contexts.
This module will support students as they consider how to seek future employment. This module will also provide students with the qualities and transferable skills necessary for employment requiring the exercise of some personal responsibility and decision making
Syllabus
The specified learning outcomes will be developed around a framework based on the following subject matter:
Carbohydrate metabolism
Carboxylic acid metabolism
Lipid metabolism
Purines and pyrimidines
Amino acid metabolism
The concepts of balance and turnover in relation to energy and non-degradable nutrients.
Energy
Nitrogen
The theory and practise of measurements with particular reference to energy and protein.
Physiological, biochemical and clinical aspects of vitamin, mineral and trace element metabolism Metabolic roles of the essential fatty acids.
Cellular generation of free radicals.
Anti-oxidants
Learning and teaching
Students will be provided with the opportunity to acquire knowledge of the subject matter through a variety of teacher led activities and self-directed study. Teacher led activities will include traditional and interactive lectures, problem solving and revision tutorials, and seminar presentations. Theoretical and practical problems will be employed to assist students in the development of their analytical and problem solving capabilities.
Students' independent learning will be encouraged through the guided use of expected directed reading of additional literature on the subject, video material and other learning resources.
Learning outcomes
On successful completion of this module students will be able to:
| 1. | Describe the main features, regulation and interconnection of key metabolic pathways in health & disease |
| 2. | Explain the concepts of balance and turnover and how energy and protein are conserved and utilized in metabolic pathways in health & disease. |
| 3. | Explain the concept of protein quality and its measurement in humans and explain established analytical techniques for the study of energy and nitrogen balance. |
| 4. | Describe the transport storage metabolism and excretion of micronutrients. |
| 5. | Interpret information from a variety of sources, including primary sources such as laboratory data and published research papers. |
| 6. | Understand how experimental evidence has been used to support theories of metabolism |
Assessment strategy
The module will be assessed by :
Presentation of a given topic about metabolic pathways. It will be a group presentation but incur an individual mark. Each students will be expected to present for 5 minutes.
Written report of 500 words which will be an account of the students individual contribution. It must be the students individual work, completed independently a making use of the from information searches gathered by the group in preparation for the presentation.
In-class tests (2 x 60 minutes). Will assess students knowledge of metabolic pathways,
Scientific report (1500 words) which will be a report of a laboratory practical to assess knowledge of measurements energy balance.
End of semester unseen exam (1x 60 minutes) Will assess students knowledge of nutritional metabolism.
The provision of formative feedback will be achieved by a formative seminar session with in class feedback.
Students must obtain at least 40% to pass this module. In addition students must normally obtain at least 35% in each component of assessment within this module. A mark of between 35% and 39% may be compensated by other components. If the module is passed on reassessment, then the maximum mark awarded will be 40%.
Learning Manager Meetings: in order to pass this module, students must attend at least two meetings with their Learning Manager (one in Autumn and one in Spring) in order to reflect upon, discuss and plan their approach to learning and organisation of their study.
| Component | Marks | Learning outcomes |
| Presentation | 15% | 1,2,5,6 |
| Written report | 15% | 1,2,5,6 |
| In class test (metabolic pathways) | 20% | 1,2,6 |
| Scientific report | 30% | 2,3,5,6 |
| End of semester unseen exam (nutritional metabolism) | 20% | 3,4,5,6 |
Bibliography
Bender DA, Bender AE (1997) Nutrition: A reference handbook. Oxford
Bender DA (2003) Nutritional Biochemistry of the Vitamins. Oxford
Bender DA. (2008) Nutrition & Metabolism. CRC Press.
Eastwood M. (2003) Principles of Human Nutrition. Oxford: Blackwell Science.
Elliot, W.H and Elliot, D.C. (2001). Biochemistry and Molecular Biology (2nd edition). Oxford
Geissler CG, Powers H (2012) Human Nutrition 12th Edn Elsevier
Gibney MJ, Macdonald IA, Roche HM (2011) Nutrition & Metabolism 2nd Edn. Blackwell.(CORE)
Groff JL, Smith JL, Gropper SS. (2005) Advanced Nutrition and Metabolism. Wadsworth/Thomson Learning.
McArdle WD, Katch FI, Katch, VL. (2004) Exercise Physiology: Energy, Nutrition and Human Performance. Philadelphia: Lippincott Williams & Wilkins
Nelson, DL & Cox, MM (2000). Lehninger Principles of Biochemistry, 3rd ed. New York: Worth Publishers.
Roach, J O'N and Benyon,S (2003) Metabolism and Nutrition (2nd edition). Mosby
Stryer, L , Berg LM, Tymoczko JL (2002). Biochemistry (5th edition). Freeman. (CORE)