module specification

Module code: NF7057
Module title: Integrated Pathology for Dietitians
This module aims to provide an appreciation of the genetic basis of inherited diseases and, wherever possible, relate disease phenotype to mutations in gene products or to aberrations in gene expression. The material covered emphasises how an understanding of human biology has advanced through the study of genetic diseases, explores the development of therapeutic strategies using up-to-date primary sources and discusses the latest technological innovations.
It reviews knowledge of human pathology and develops understanding of the research interface, emphasizing the ability to evaluate, integrate and debate topical issues in aetiology, epidemiology or pathogenesis and treatment of disease.
This module will provide learners with a critical understanding of the aetiology, pathology, medical, pharmacological and surgical management of a range of diseases including HIV, renal, liver, cancer and those of the GI tract and respiratory systems.
Assessment: Oral presentation (15 minutes) (40%); Unseen exam (1.5 hours) (60%)
This module forms an essential part of practice based learning preparation. Learners must obtain at least 50% to pass this module. In addition learners must usually obtain at least 45% in each component of assessment within this module. A mark of between 45% and 49% may be compensated by other components.

The information provided in lectures and tutorials together define;
the causes of cell injury, alteration and death, describing the structural and functional change in disease at molecular and tissue levels. LO1, LO2
·the aetiology, consequences and monitoring of bacterial and major parasitological diseases including the action of classes and individual important toxins.
routine, specialist and research methodologies available to the health and human scientist in the context of selected exemplars. LO1, LO2, LO3
the structural and functional changes in respiratory and alimentary disease.
the origin and development of cardiovascular disease and atherogenesis, mitochondrial myopathies and other inherited myocardial defects, discussing the evaluation of lipoproteins, apoproteins, homocysteine, cardiac enzymes, myeloperoxidase  as biomarkers in atherosclerosis and myocardial infarct. LO1, LO2
selected endocrine disorders including diabetes, discussing causes, classification, consequences and indicators such as fructosamine and C fragment peptide. LO1, LO2
the genetic–epigenetic interface in tumour biology, describing  oncogenes, tumour suppressor genes, cell cycle control, tumour classification, grading  and staging, as well as metastasis and  biochemical markers of disease spread.
Drug nutrient interactions LO1, LO2, LO3
The classifications of medicines and medicines management, including the role of the dietitian and healthcare scientist. LO1, LO2, LO3
The use of and evidence underpinning complementary and alternative medicine. LO1, LO2, LO3
Interprofessional learning where learners will have opportunity to learn with and from healthcare science learners LO1, LO2, LO3

Learners knowledge and understanding of Integrated Pathology will be developed through a programme of lectures (constituting some 22 hours of study), tutorial and supporting practical exercises (18 hours), including some problem-based approaches and the guided use of learner centred learning resources. Lectures will be used to provide a conceptual framework. Learner centred assignments, including research for the seminar (160 hours) will enable learners to reinforce and expand their knowledge and develop subject skills, presentation and competence.

On successful completion of this module learners will:
1. Appraise and justify the medical, pharmacological and surgical management of range of diseases and explain the aetiology, pathology and diagnosis of disease.
2. Critically evaluate current clinical guidelines for a given disease
3. Demonstrate an awareness of core professional skills required to support practice on Practice based learning 2 and 3.

Assessment will comprise:
1. An oral presentation (15 minutes) (40%) (learning outcomes 1,2, 3). Learners will work in groups of two or three to present their findings of a critical appraisal of one set of clinical guidelines using a standard appraisal tool. Learners will individually present in pairs for 15 minutes in total; 10 minutes each and 5 minutes for questions
2. Unseen Exam (90 minutes) (60%) (learning outcomes 1,2,3)

This module forms an essential part of practice based learning preparation. Learners must obtain at least 50% to pass this module. In addition learners must normally obtain at least 45% in each component of assessment within this module. A mark of between 45% and 49% may be compensated by other components.

Recommended Books;
Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K. and Walter, P. (2007). Molecular Biology of the Cell. 5th edition. Garland.
Howard, R. A. and  Hamilton, P. J. (2008). Haematology, An Illustrated Colour Text. 3rd edition. Churchill Livingstone.
Innes JA (Ed) Davidson’s Essentials of Medicine (2015) Churchill Livingstone (CORE)
Jones, A., Reed, R. and Weyers, J. (2003). Practical Skills in Biology.  3rd edition. Prentice Hall.
Kumar, V., Abbas, A.K.,Aster J. (2014). Pathologic Basis of Disease.   9th edition. Elsevier (CORE)
Lydyard, P., Lakhani, S., Dogan, A., Holton, J., Patterson, K., Bolodeoku, J. and  Playfair, J. (2000). Pathology Integrated. An A-Z of Disease and Its Pathogenesis. Arnold.
Macdonald, F., Ford, C. H. J. and Casson, A. G. (2004) Molecular Biology of Cancer.  2nd edition,  Garland/Bios Scientific Pub.
Marshall, W. and Bangert, S. K. (2004). Clinical Chemistry, 5th edition. Souhami, R.L and Moxham, J. eds.Textbook of Medicine. 4th edition. Elsevier.
Mitchell R, Kumar V, Fausto N, Abbas A.K. (2010). Pocket Companion to Robbins and Cotran Pathologic Basis of Disease. 7th edition, Elsevier Inc. 
Innes JA (Ed) Davidson’s Essentials of Medicine (2015) Churchill Livingstone

Social Media Sources:
LondonMet NutSoc @Londonmetnutsoc
Nutrition London Met @DFNLondonMetUni

Online resources:
BMJ Best practice [electronic resource]
accessed via the university library:
http://catalogue.londonmet.ac.uk/search/?searchtype=X&searcharg=bmj+best&searchs
cope=1&sortdropdown=r