BE5061 - Human Immunity (2019/20)
|Module specification||Module approved to run in 2019/20|
|Module title||Human Immunity|
|Module level||Intermediate (05)|
|Credit rating for module||15|
|School||School of Human Sciences|
|Total study hours||150|
|Running in 2019/20||
This module provides an introduction to physiological, cellular and molecular fundamentals of human immunology. It includes consideration of innate and acquired immune defences, genetic variation and immune defence, and immune responses or involvement in a range of pathological conditions. The aims of this module are aligned with the qualification descriptors within the Quality Assurance Agency’s, Framework for Higher Education Qualifications.
The module integrates the knowledge and skills acquired from other modules, and encourages independent learning through the access of information using appropriate laboratory, primary and secondary sources, and informatics resources. It develops competence in laboratory skills through practical work, and in scientific writing. It aims to develop students’ qualities and transferable skills necessary for employment including developing ability to solve problems, and gather and interpret data to inform a focussed theme and writing reports. Moreover students have an opportunity to develop self-management employability skills by engaging fully with the learning material and opportunities made available to them, and by continually reflecting on their progress through the module using the regular feedback opportunities available to them.
Prior learning requirements
The module is an introduction to immunology that starts with an overview of the systems of the body that provide defence against infection. Key types of immune cell are reviewed, followed by a comparison of innate and acquired immune defences.
Key types of molecules utilised by the immune system are reviewed including antibodies, the major histocompatibility complex, T-cell receptors, complement, signalling molecules such as cytokines, and innate defence molecules. The mechanisms, and genetic basis, of immune diversity will be reviewed. Immune responses to infection, and immune involvement in a range of pathological conditions will be addressed. LO1,LO2,LO3
Balance of independent study and scheduled teaching activity
Acquisition of knowledge of the subject matter of this module will be promoted through lecturer-led lectures (18h), associated small-group tutorials (9h) and module review (2h). These will be supplemented with the guided use of web-based student-centred learning resources, including web-based directed study and review (34 hours). Each lecture has an associated tutorial class and web-based review in the form of an MCQ test (formative assessment). Links to selected web resources are also provided within individual sessions. Practical classes (6 hours) will be used to develop laboratory skills and to consolidate knowledge in applied aspects of immunology. Students are expected to complete a short report to hand in at the end of each class (formative assessment), which will include opportunities for reflective learning. The remaining time is self managed for private study (81 hours)
On successful completion of this module students will be able to:
1. Show an appreciation of the basic mechanisms of immune responses, including the physiological responses, the types of cells and molecules involved;
2. Procure or generate, assess and interpret data obtained from a variety of resources including laboratory work, primary and secondary literature and relevant databases;
3. Extract, collate, analyse and summarise data on a focussed topic to develop report writing as an employability skill (Communication and Literacy).
Assessment is designed to promote deep learning through regular formative and summative assessment with quizzes throughout the module (20%). The highest marks from three quizzes, will be included in the Quizzes component of the module mark. A reassessment quiz will cover material tested in the semester’s quizzes. An end of module unseen exam (1h 40%) will assess knowledge acquired through the semester. The coursework component is a report written from information from primary and secondary literatures sources and informatics databases (40%; 1500 words). Criteria for assessment will include an understanding of the subject matter; an ability to explain, describe and discuss the work; completeness and conciseness of written reports and essays with emphasis upon critical ability and scientific rigour.
To pass the module, students need to achieve a minimum aggregate mark of 40%. There will be an attendance requirement for the practical sessions. If the module is passed on reassessment, then the maximum mark awarded will be 40%.
Component Marks Learning outcomes
Written report 40% 1, 2, 3
Exam 40% 1, 2
Quizzes 20% 1, 2
Practical Attendance 0%
ABBAS, A.K., LICHTMAN, A.H. and PILLAI, S. (2014) Basic Immunology: functions and disorders of the immune system. 4th ed. Philadelphia: Elsevier/Saunders.
COICO, R. and SUNSHINE, G. (2015) Immunology: a short course. 7th ed. John Wiley [ONLINE]
DELVES, P.J., MARTIN, S.J., BURTON, D.R. and ROITT, I.M. (2017) Roitt’s essential immunology. 13th ed. John Wiley [ONLINE]
GEHA, R. and NOTARANGELO L. (2012) Case studies in immunology. 6th ed. London: Garland Science.
OWEN, J.A., PUNT, J., STRANFORD, S.A. and JONES, P.P. (2013) Kuby Immunology. 7th ed. New York: Freeman.
PLAYFAIR, J.H.L. and CHAIN, B.M. (2013) Immunology at a Glance. 10th ed. Chichester: John Wiley. [ONLINE]