module specification

This module provides an understanding and knowledge of the theory and practice of transfusion and transplantation. It addresses the identification of blood groups and antibodies, other haemopoetic cell antigens and their clinical significance, the safe supply of blood and blood products, the principles of stem cell and solid organ transplantation, tissue and bone banking, organ transplantation, prophylaxis and immunotherapy, and quality issues

None

Immunology related to transfusion and transplantation practices, Blood grouping principles and significance, antibody screening, Blood donation, blood components, clinical transfusion, HLA, HPA, HNA and their significance, haemolytic disease, transfusion transmitted infections, Stem cell transplantation, and solid organ transplantation.

Learning Outcomes LO 1 - 4

Information pertaining to the subject matter will be presented through an integrated programme of lectures and supporting exercises, together with some use of a problem-based learning approach and the guided use of student-centred learning resources.  Lectures will be used to provide a conceptual framework.  Student centred assignments will enable students to reinforce and expand their knowledge, and develop subject specific skills and competence.

On successful completion of this module students will be able to:
1. Identify the important features of the different blood group systems, haemostasis and be familiar with the procedures involved with the safe use of blood products and relate transfusion theory to laboratory and clinical practice;
2. Develop a working knowledge of the principles and practice of transfusion
Science, discuss indication for the use of blood component therapy and identify and discuss in-depth the clinical aetiology and management of immunohaematological and transplantation disorders;
3. Demonstrate through the written assignment an understanding of blood donation, collection, screening and
Storage and describe the role of biomedical scientists in maintenance of transfusion or transplantation laboratory services.
4. Demonstrate through the reflective learning journal that the student has reflected on their own performance as an independent professional learner.

The module will be formatively assessed by in-course online quizzes and two coursework components. A reflective learning log (1000 words) and a written assignment (1000 words). Criteria for assessment will include an understanding of the subject matter; an ability, both orally and written, to explain, describe and discuss the work; completeness and conciseness of written reports and essays with emphasis upon critical ability and scientific rigour. To pass the module students need to achieve a minimum aggregate mark of 50%. There are no practical sessions.

Component                  Learning outcomes
Quizzes                                    1
Reflective learning log             1,2
Written assignment                  3,4

Contreras M. Ed. (2009) ABC of Transfusion 4th Ed. British Medical Journal.

Daniels G, Bromilow I. (2013) Essential Guide to Blood Groups. Blackwell.
Avent N. (2018) Transfusion and Transplantation Science. Oxford University Press.
Lederer SE. (2008) Flesh and Blood: Organ transplant and blood transfusion in 20th century America. Oxford University Press
Bain B J, Bates I. (2016) Dacie and Lewis Practical Haematology. Churchill Livingstone.
Delves PJ, Martin SJ (2017) Roitts Essential Immunology. Mosby.
Murphy MF, Pamphilon DH. (2017) Practical Transfusion Medicine Blackwell.