BC6059 - Genomics (2022/23)
|Module specification||Module approved to run in 2022/23|
|Module level||Honours (06)|
|Credit rating for module||15|
|School||School of Human Sciences|
|Total study hours||150|
|Running in 2022/23(Please note that module timeslots are subject to change)||
This module provides information and guidance to facilitate an understanding and knowledge of the theory and practical applications of molecular biology, genetics and genomics. It explains the underlying mechanisms of molecular biology and enables these ideas to be expanded to the understanding of human health and disease.
To provide, thorough in depth study, knowledge and understanding of the theory and practical applications of the underling molecular biology of modern genetics and genomics. This module will investigate both historical and modern approaches to genomics. It will reinforce analytical, evaluative and communication skills. The module will also enable students to research a topical issue in depth and present it and reflect on the topics studied and their application in biomedical practice.
Prior learning requirements
Review of the basis of molecular biology and genetics.
Study the developments in genomes and genetics
Mechanics of DNA replication, transcription and translation. (1-3)
Genomic technology, DNA in forensics. Discussion of ethical issues involved in Genetic testing and screening; development and use of gene therapies. And 3rd generation sequencing (3)
Balance of independent study and scheduled teaching activity
Students will be guided by staff in their learning using a combination of private study, interactive lectures, novel investigative practicals and small group tutorials exploring realistic problems/case studies. Preparation for assignments will enable students to reinforce and expand their knowledge base and develop subject skills and competences. They will be able to assess and reflect upon their understanding of the fundamental material through the completion of on-line quizzes.
On completion of this module students’ provide an evaluation of how the module enabled them to develop skills such as information technology, organisational skills, team building, communication, time management and working under pressure.
On successful completion of this module students will be able to:
1. understand inheritance patterns in human pedigrees and the processes of mutation detection by genomic techniques and the consequences of various genomic mutations and polymorphisms in health and disease;
2. analyse and solve molecular biological, genetic and genomic problems
3. Use numerical formulae to assess parameters such as the Hardy Weinberg equilibrium; allele frequency and genetic and physical distance between genomic markers and recognise and explain changes in gene structure or expression and in terms of the development of disease phenotype
The module will be summatively assessed by the completion of a practical report on a selected genetic topic and by a portfolio reflecting on current reading and seminars..
To pass the module students must achieve a minimum aggregate mark of 40%