BM7108 - Introduction to Molecular Biology and Genetics (2023/24)
| Module specification | Module approved to run in 2023/24 | ||||||||||||||||
| Module title | Introduction to Molecular Biology and Genetics | ||||||||||||||||
| Module level | Masters (07) | ||||||||||||||||
| Credit rating for module | 10 | ||||||||||||||||
| School | School of Human Sciences | ||||||||||||||||
| Total study hours | 100 | ||||||||||||||||
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| Running in 2023/24(Please note that module timeslots are subject to change) |
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Module summary
This module provides information and guidance to faciliatate an indepth understanding and knowledge of the theory and practical applications of molecular biology and genetics. It explains the underlying mechanisms of molecular biology and enables these ideas to be expanded to the understanding of human health and disease.
Prior learning requirements
None
Syllabus
Review of the basis of molecular biology and genetics.
Study the vast developments in genomes and genetics
Mechanics of DNA replication, transcription and translation.
Genetic technology, DNA in forensics and genetics in cancer.
Learning Outcomes LO 1 - 3
Balance of independent study and scheduled teaching activity
Information pertaining to the subject matter will be presented through an integrated programme of lectures and supporting exercises, together with some use of a problem-based learning approach and the guided use of student-centred learning resources. Lectures will be used to provide a conceptual framework. Student centred assignments will enable students to reinforce and expand their knowledge, and develop subject specific skills and competence.
Learning outcomes
On successful completion of this module students will be able to:
1. Demonstrate an understanding of the processes of mutation detection by
molecular biological techniques and show an understanding of the consequences of various mutations and polymorphisms in health and disease through completion of the quizzes
2. Apply critical thinking to the analysis and solve molecular biological and
genetic problems and show an appreciation of current and evolving concepts in molecular biology and genetics specifically gene therapy and forensic applications.
3. Demonstrate through the reflective learning journal that they have reflected on their own performance as an independent professional learner
Assessment strategy
The module will be formatively assessed by in-course online quizzes and two coursework components. A reflective learning log (1000 words) and a written assignment (1000 words). Criteria for assessment will include an understanding of the subject matter; an ability, both orally and written, to explain, describe and discuss the work; completeness and conciseness of written reports and essays with emphasis upon critical ability and scientific rigour. To pass the module students need to achieve a minimum aggregate mark of 50%. There are no practical sessions.
Component Learning outcomes
Quizzes 1
Reflective learning log 2
Written assignment 2,3
Bibliography
Carroll SB, Doebley J. (2015) Introduction to Genetic Analysis WH Freeman.
Hartl DL. (2012) Essential Genetics: A Genomics Perspective Jones and Bartlett.
Jorde LB, Carey JC, (2015) Medical Genetics 4th Ed. Mosby.
Berk A, (2016) Molecular Cell Biology. WH. Freeman
Read A, Donnai D. (2015) New Clinical Genetics. Scion.
Reed R, Weyers J, (2016) Practical Skills in Biomolecular Sciences, OUP
Gibson G, Muse SV. (2009) A Primer of Genome Science 3rd Ed. Sinauer Associates.
Strachan T, Read A. (2011) Human Molecular Genetics 4th Ed. Garland Science.